Stefanchik bunted her way on with one out and Gordon followed with a single to left to give Harvard runners at first and second.
That set the table for Fritsch, who walloped a shot over the left field fence for her third home run of the season and three more RBI.
Bettinelli kept the inning going with a single to center, advancing to second on a sacrifice bunt from Halpenny. Williamson knocked in Bettinelli with a double down the left field line and gave the Crimson a 4-0 lead.
Brotemarkle then did what comes natural to her, setting Bulldog batters down time after time, aided by the pitch calling of Halpenny.
“Our offense really came through and got us a good cushion, so we could relax a little on the field,” Brotemarkle said.
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Harvard added two more insurance runs, superfluous with Brotemarkle on the mound, in the sixth and seventh innings.
Stefanchik and Fritsch both went 3-for-4, and Williamson and Gordon batted 2-for-4 on the day.
The Crimson face cross-town rival Boston College on Thursday at Chesnut Hill, and then will play host to Dartmouth on Saturday for its final Ivy doubleheader.
—Staff writer J. Patrick Coyne can be reached at coyne@fas.harvard.edu.