He said, at present time, he has no intention to run for president.
"You have to want the job. And I don't want the job," he said.
Still, as the Reform Party's highest-ranking elected official, Ventura holds significant sway over whom the party decides to nominate.
Ventura is said to be intrigued by the candidacy of real estate mogul Donald Trump, and much less enamoured about the prospect of Pat Buchanan joining his party.
Asked by CNBC's Matthews about being in the same party with Buchanan, Ventura responded, "No, we're not, no, we're not."
Matthews began another Hardball segment by attempting to induce Ventura to elaborate on comments he made about the assassination of John F. Kennedy '40.
Ventura told Playboy that he thought the "military-industrial complex" killed the popular president in 1963.
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