Another challenge, according to Baker, is countering the proliferation of weapons of mass destruction in countries such as North Korea, Iran, Iraq and Libya.
"Simple possession of these weapons allows them to blackmail their neighbors and the international community," Baker said.
Creating stronger non-proliferation treaties, enforcing strict sanctions against such nations and controlling the transfer of technology and raw materials from developed nations are some of the proposals Baker made to address the problems he outlined.
He added that one of the most vital ways to maintain sound foreign policies abroad is to strengthen U.S. domestic sentiments towards international involvement.
"Today's political climate is, in many ways, indifferent, if not hostile, to American leadership abroad," Baker said. "We need to re-invigorate the need for bi-partisanship in international issues."
One audience member expressed his belief that Baker was particularly well-situated to observe U.S. foreign policy.
"It is interesting to hear the view-point of somebody who is not in government anymore," said Erik A. Johnson, a student at the Fletcher School of Law and Diplomacy at Tufts University