Bundy, who dropped out of law school after a year, is believed to have stalked young women near college campuses, shopping centers and parks in the West and Northwest, targeting those with long, dark hair, parted in the middle.
Prosecutors said he often lured victims into his car by posing as a police officer or making false requests for aid.
One of the women he admitted killing was Caryn Campbell, 23, of Dearborn, Mich., who was killed by a blow to the head while vacationing in Colorado in 1975.
"You never really forgive someone for something like that. You just try to put it behind you," her father, Robert Campbell, said Monday. "It's not important to me now. The thing I'd like to have back, I can't have."
Bundy's final appeals, including a series to the U.S. Supreme Court, were rejected Monday.
The execution was the 20th in Florida since it resumed executions in 1979; 106 murderers have been put to death in the United States since capital punishment was restored in 1976.
Bundy, who grew up in Tacoma, was linked to three dozen killings of young women. As the execution approached, he met with investigators from Western states and admitted killing eight women each in Washington and Utah and two each in Colorado and Idaho, authorities said.