Robert G. McCloskey, professor of Government, yesterday urged the defeat of all Republican candidates who have not repudiated the Goldwater-Miller ticket.

"I suggest that there should be a heavy presumption against any candidate who bears the Republican tag in 1964," he wrote in a letter to the New York Times. "The party as a whole must be punished for what it did at San Francisco... to make sure that such an offense is not committed again."

McCloskey added that the Republicans had risked the nomination of "an extreme right candidate" because they felt that any Republican candidate for President would be defeated. He said that they chose to ignore the possibility that "an extremist candidate might lose so badly as to pull down secondary Republican candidates in his wake."

"Our problem is to convince them that they were wrong to ignore it, and to discourage them from such temptations in the future," McCloskey stated. "The deterrent lesson can only be learned by defeating the Republicans in 1964 in whole-sale lots."

McCloskey did not mention Republican candidates who have refused to support the Goldwater-Miller ticket, but said that "each voter must decide for himself whether the general presumption against Republicans is, as the lawyers say, rebuttable in an individual case."